The Global Sepsis Alliance is a non-profit charity organization with the mission to provide global leadership to reduce the worldwide burden of sepsis. The GSA is the initiator of World Sepsis Day on September 13 and World Sepsis Congress, a series of free online congresses bringing knowledge about sepsis to all parts of the world, among other initiatives.

The GSA works closely with its over 100 member organizations, patient advocacy groups, professional societies, healthcare authorities, and governments to implement changes on how sepsis is prioritized, diagnosed, and treated all around the world, as laid out by the WHO Resolution on Sepsis.